Bone Marrow Transplant Unit
Advanced infrastructure excelling in Bone Marrow Transplant
Seamless support from diagnosis to post treatment care
Advanced Pediatric Bone Marrow Transplants at Rainbow Children's Hospital
A bone marrow transplant involves the replacement of bone marrow responsible for generating new blood cells. Pediatric blood disorders, while not always malignant, can profoundly impact a child's quality of life and, in certain cases, pose a fatal threat.
Conditions like childhood anemia, iron deficiency anemia, iron-refractory iron deficiency anemia, congenital sideroblastic anemia, and congenital dyserythropoietic anemia can be effectively treated through bone marrow transplants. Additionally, children with specific types of cancer and blood disorders, such as sickle cell disease, leukemia, and thalassemia, can find significant benefits from this procedure.
The bone marrow transplant is a complex and major medical undertaking, demanding the utmost care and specialized oncological expertise. At Rainbow Children's Hospital, our distinguished team of Pediatric Oncologists, Hematologists, and super specialists has garnered renowned for their extensive experience in performing over 70 successful Best Bone Marrow Transplants.
Our Bone Marrow Transplant Unit (BMTU) at Rainbow Children’s Hospital offers comprehensive services, including:
1. In-house blood bank facility.
2 .RO water supply for all purposes.
3. High-efficiency particulate air module (HEPS) filters, maintaining positive air pressure and filtering particles within the BMTU unit.
4. A laminar hood for the sterile preparation of medications.
5. Pass boxes for the sterilization of items like food before entering the BMTU.
6. 24/7 availability of doctors and one-to-one barrier nursing to ensure a high success rate.
Key Highlights:
1. Specialises in handling high risk cancer & non-malignant conditions that are curable with stem cell transplants
2. Specially trained nursing staff well versed with handling various procedures, preparations & other nursing aspects to provide quality care to patients
Find a Doctor
Expertise you can trust, Meet our esteemed doctors who bring exceptional knowledge, compassion, and innovation to provide top-notch care for your health and well-being.
Dr. Sirisha Rani
Sr. Consultant- Pediatric Hematologist & Oncologist, BMT
20 Years English,Hindi,Kannada,Tamil,Telugu Banjara Hills, Currency Nagar, Health City
Dr. Vasudha N R
Consultant- Pediatric Hematologist, Oncologist & BMT Physician
English,Kannada,Marathi,Telugu Marathahalli, Hebbal
Dr. Manojit Chakraborty
Consultant - Paediatric Hematology, Oncology & Bone Marrow Transplant
10 Years Assamese,Bengali,English,Hindi,Kannada,Marathi Marathahalli, Bannerghatta, Sarjapur Road, Guwahati
Dr. Meena Sivasankaran
Consultant - Pediatric Hemato Oncology
8+ Years English,Hindi,Tamil Guindy
Dr. Nandini Choudhury Hazarika
Consultant - Medical Oncology, BMT
English,Hindi Malviya Nagar
Dr. Nalla Anuraag Reddy
Consultant - Pediatric Hematologist, Oncologist, Blood & Marrow Transplant Physician
8 Years English,Hindi,Kannada,Tamil,Telugu Banjara Hills, Hydernagar, Financial District
Dr. Sandhya Vaddadi
Consultant Hematology & Oncology, BMT
8 Years English,Hindi,Kannada,Telugu Secunderabad, Banjara Hills, Currency NagarOur Hospitals and ClinicsOur Hospitals and Clinics
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25 Years of Compassionate Care
25 Years of Anniversary - Rainbow Children's Hospital & BirthRight
Hi9 | Warning Signs of heart diseases in kids | Dr. Sri Phani Bhargavi
Understanding Hereditary Heart Issues in children | Dr. Sri Phani Bhargavi Dhulipudi
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Childcare during the rainy season discussed by Dr. Dinesh Kumar - Rainbow Children's Hospital
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FAQs
What is bone marrow and why is its health important for children?
Bone marrow is the soft, spongy tissue found inside bones that produces red blood cells, white blood cells, and platelets. Damage to the bone marrow impairs the body's ability to fight infections and diseases, a condition known as immune deficiency or immunosuppression. For children with bone marrow disorders, early specialist evaluation is essential. Rainbow Children's Hospital offers expert Pediatric Hematology and BMT consultations to assess and treat bone marrow conditions in children.
What is a Bone Marrow Transplant and how is it performed in children?
A Bone Marrow Transplant is a procedure in which the stem cells that produce the blood are transferred intravenously into the patient. During the procedure, the transplant will be replacing the missing or defective marrow. It is also used on children that have gone through radiation or high dose chemotherapy.\n\nStem cells are first taken from a donor from either the bone marrow, the umbilical cord blood, or the circulating peripheral blood. These stem cells will be transfused into the bloodstream of the patient. The cells will find their way to the marrow spaces of the bone. Once they reach there, they will start growing and multiplying and repopulating the bloodstream with RBCs, WBCs, and platelets. best hospital for bone marrow transplant in India and best hospital for bone marrow transplant in Bangalore provides the best treatment for Bone Marrow Transplantation. :12929, 3,, 15 Merriweather A Bone Marrow Transplant is a procedure in which the stem cells that produce the blood are transferred intravenously into the patient. During the procedure, the transplant will be replacing the missing or defective marrow. It is also used on children that have gone through radiation or high dose chemotherapy.
Stem cells are first taken from a donor from either the bone marrow, the umbilical cord blood, or the circulating peripheral blood. These stem cells will be transfused into the bloodstream of the patient. The cells will find their way to the marrow spaces of the bone. Once they reach there, they will start growing and multiplying and repopulating the bloodstream with RBCs, WBCs, and platelets. best hospital for bone marrow transplant in India and best hospital for bone marrow transplant in Bangalore provides the best treatment for Bone Marrow Transplantation."
When does a child need a Bone Marrow Transplant?
A child may require a Bone Marrow Transplant in three clinical situations:
• Bone marrow failure - when abnormal or absent blood cells must be replaced by functional stem cells to restore immune function.
• Cancer treatment - when stem cells destroyed by high-dose chemotherapy or radiation therapy need to be replenished.
• Genetic disorders - when defective or absent cells originating in the bone marrow must be corrected through transplantation.
At Rainbow Children's Hospital, Pediatric Hematologists and Oncologists assess each child's condition to determine the most appropriate transplant approach.
What conditions can be treated using a Bone Marrow Transplant?
Here are some of the conditions that require a Bone Marrow Transplant: Acute Lymphocytic Leukemia (ALL) Acute Myelogenous Leukemia (AML) Adrenoleukodystrophy (ALD) Aplastic anemia Brain tumors Chronic Lymphocytic Leukemia (CLL) Chronic Myelogenous Leukemia (CML) Epidermolysis Bullosa Ewing's sarcoma Fanconi Anemia Globoid cell Hodgkin's disease Hurlers syndrome Immune deficiency Juvenile Myelomonocytic Leukemia (JMML) Krabbe’s Disease Maroteaux-Lamy syndrome Metachromatic Leukodystrophy (MLD) Multiple Myeloma Myelodysplastic Syndrome (MDS) Neuroblastoma Non-Hodgkin's lymphoma Osteopetrosis Renal cell carcinoma Sickle Cell Anemia Thalassemia
What are the different types of stem cell transplant used in Pediatric BMT?
There are three forms of stem cell transplant used in Pediatric BMT:
• Allogeneic - stem cells are taken from a human leukocyte antigen (HLA)-matched donor, who may be a related or unrelated individual
• Autologous - the child's own stem cells are collected before a conditioning regimen and reinfused after the procedure
• Syngeneic - stem cells are sourced from the child's identical twin
The appropriate transplant type is determined by the child's diagnosis and donor availability. Rainbow Children's Hospital offers all three forms of pediatric stem cell transplant through its dedicated Bone Marrow Transplant Unit.
How and from where are stem cells harvested for a Bone Marrow Transplant?
Stem cells for a Bone Marrow Transplant can be harvested through three methods:
• Hip bone (iliac crest) - blood is collected from the centre of the marrow space under anaesthesia
• Peripheral blood - intravenous catheters filter the bloodstream to collect circulating stem cells
• Cord blood - umbilical cord blood donated at birth and stored in a stem cell registry is used; it is rich in hematopoietic stem cells
The harvesting method is selected based on the transplant type and donor availability. Rainbow Children's Hospital's BMT team manages the full harvesting and transplantation process for each child.
What are the risks involved in the Bone Marrow Transplant?
A Bone Marrow Transplant carries several known risks that are closely monitored by the specialist team throughout the procedure:
• Organ complications - the heart, kidneys, lungs, and liver may be affected and require continuous monitoring
• Infection - a weakened immune system increases susceptibility to bacterial, fungal, and viral infections; preventive medications and Cytotoxic T Lymphocytes (CTLs) may be used
• Mucositis - chemotherapy-related inflammation of mucous membranes in the mouth, throat, and gastrointestinal tract; pain and palliative services reduce discomfort
• Graft-Versus-Host Disease (GVHD) - the immune system may react to the donor graft; managed with immunosuppressive medications
• Thrombotic Microangiopathy (TMA) - inflamed blood vessels causing clots, elevated blood pressure, and potential kidney injury
At Rainbow Children's Hospital, each risk is proactively managed by an experienced Pediatric BMT team.
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